Wheat: Much More Than You Wanted To Know

The exhaustive review of wheat: it weighs the anti-wheat claims (non-celiac gluten sensitivity, leaky gut, gliadin-derived opiates, autism/schizophrenia links, "genetic modification", the lectin-leptin theory) against the pro-wheat evidence, concluding that wheat is probably fine for most people most of the time - while honestly flagging the genuinely uncertain leaky-gut/autoimmune thread and the puzzling anecdotal reports (including his own) of feeling better off wheat.

Quality 74 · Strong. A model evidence-synthesis - balanced, numerate, candid about confounders (whole vs. refined grain) and the limits of the data. A notch below the Marijuana MMTYWTK because it lacks a single striking analytic reframe. Top of Strong.

Claude’s paradigm shift 28 · Slight. A careful review of a popular-diet question; introduces no new concept or frame. Slight.

Real-world impact 2 · Minor. A model evidence-synthesis weighing the anti-wheat claims against the data and concluding wheat is probably fine for most, while honestly flagging the uncertain leaky-gut thread. Real topical relevance to diet/health, but a balanced review informing understanding with no material change — low RWI.